A nature-based proposal from an ancient grainD-Fagomine is a non-digestible glucose analog. It was discovered andfirst isolated from buckwheat in 1974 but it was not until a few yearsago when started doing tests onits biological activity, and thenunderstand its functionalities. Buckwheat contains a number ofrelevant active substances andonly recent research has shownthat the D-fagomine presence inbuckwheat is behind much of thehealthy benefits relatedtraditionally to buckwheat foodconsumption. D-Fagomine is a friendly Secon-dary Metabolite witch is specially beneficial for the the plant. Thismetabolite protects the grain by inhibiting competitively third partiesglycosidases and giving an advantage to the buckwheat grain to staywhole longer. In human diet, D-fagomine has been shown to decreasepostprandrial blood glucose level without stimulating insulin secretion.As such D-fagomine has been proposed as a useful dietary ingredient orfunctional food component to reduce the health risks associated with an excessive intake of fast-digestible carbohydrates. The most recent research on the substance is showing aditional sinergicmolecular mechanisms of D-fagomine activating the immune cells andmodulate microbiome, encouraging the growth of some beneficialspecies by reducing the presence of agressive sugar hungry species. D-fagomine research represents nowadays one of the most innovativeareas of development in nutrition to get and mantain a healthymicrobiome that might be easily translated to the market because of itspresence in the human food chain. Also the research on this dietarysubstance are opening novel scientific ways to overcome some of theimmune-mediated inflammatory diseases (autoimmune diseases) thatare very prevalent nowadays. Healthy Traditional FoodThere is a positive feeling of healthy food linked to buckwheat. Thisgrain is usually related to an historical consumption in times of famine,keeping people healthy. It is present in almost all the countries in theNorth Hemisphere where this grain grows spontaneously in clearings ofthe forest, and where it has been also cultivated for centuries.Many traditional foods are based on this healthy grain. Buckwheat isused to prepare different foodstuffs such as noodles (Japanese soba,Korean makguksu, or Italian pizzoccheri), groats (Polish Kasha),pancakes (French crêpes de Bretagne, Slavic blinis, or North Americanployes), boiled flour (Italian polenta or Slovenian and Croatian žganci),fried dough (Spanish farinetes de fajol from Catalonia), beer, biscuits orcookies, bread and a myriad of other healthy home recipes.Contact us !!! We are walking the way to improve the awareness of D-fagomine nutritional benefits to the nutritional society and also to the food & health players.If you are a health professional, nutrition expertfrom Industry, Academia or Administration we inviteyou to contact us to be updated on the technicaladvances and to discuss the way we can cooperateto accelerate the communication and launch intothe market of novel proposals based on the present knowledge and available intelectual property. @